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This paper focuses primarily on the interplay among environmental factors, homeostatic mechanisms of eating (such as leptin and ghrelin), and emotional/cognitive factors. Figure 1 presents a flow chart of the complex network that regulates feeding behavior and energy balance. The main conclusion states that in obese subjects, the homeostatic mechanism that usually prevents mammals from over-eating has been superseded by environmental signals. Overall, the authors of this paper believe that there is a need for more research regarding the interactions between the cortico-limbic circuit and the hypothalamus - a suggestion that we also make in our conclusion.

Return to Neural Reward, Energy Homeostasis, and Addiction-like Compulsive Eating

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